Trabajos de Manuel Hidalgo

Trabajos de Nombre

Clinical Medicine

Listando 49 trabajos del autor/autora 38

Lista de trabajos en el área Clinical Medicine

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Article Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF Teresa Blasco, Maria; Navas, Carolina; Martin-Serrano, Guillermo; Grana-Castro, Osvaldo; Lechuga, Carmen G.; Martin-Diaz, Laura; Djurec, Magdolna; Li, Jing; Morales-Cacho, Lucia; Esteban-Burgos, Laura; Perales-Paton, Javier; Bousquet-Mur, Emilie; Castellan CANCER CELL 1535-6108 (2019) DOI / 10.1016/j.ccell.2019.03.002 Green accepted, Bronze

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Article BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial Bockorny, Bruno; Semenisty, Valerya; Macarulla, Teresa; Borazanci, Erkut; Wolpin, Brian M.; Stemmer, Salomon M.; Golan, Talia; Geva, Ravit; Borad, Mitesh J.; Pedersen, Katrina S.; Park, Joon Oh; Ramirez, Robert A.; Abad, David G.; Feliu, Jaime; Munoz, Andr NATURE MEDICINE 1078-8956 (2020) DOI / 10.1038/s41591-020-0880-x

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Article CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma Salvador-Barbero, Beatriz; Alvarez-Fernandez, Monica; Zapatero-Solana, Elisabet; El Bakkali, Aicha; del Camino Menendez, Maria; Lopez-Casas, Pedro P.; Di Domenico, Tomas; Xie, Tao; VanArsdale, Todd; Shields, David J.; Hidalgo, Manuel; Malumbres, Marcos CANCER CELL 1535-6108 (2020) DOI / 10.1016/j.ccell.2020.01.007 Bronze

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Article c-RAF Ablation Induces Regression of Advanced Kras/Trp53 Mutant Lung Adenocarcinomas by a Mechanism Independent of MAPK Signaling Sanclemente, Manuel; Francoz, Sarah; Esteban-Burgos, Laura; Bousquet-Mur, Emilie; Djurec, Magdolna; Lopez-Casas, Pedro P.; Hidalgo, Manuel; Guerra, Carmen; Drosten, Matthias; Musteanu, Monica; Barbacid, Mariano CANCER CELL 1535-6108 (2018) DOI / 10.1016/j.ccell.2017.12.014 Bronze

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Article Phase I/II Trial to Evaluate the Efficacy and Safety of Nanoparticle Albumin-Bound Paclitaxel in Combination With Gemcitabine in Patients With Pancreatic Cancer and an ECOG Performance Status of 2 Macarulla, Teresa; Pazo-Cid, Roberto; Guillen-Ponce, Carmen; Lopez, Rafael; Vera, Ruth; Reboredo, Margarita; Munoz Martin, Andres; Rivera, Fernando; Diaz Beveridge, Roberto; La Casta, Adelaida; Martin Valades, Jose; Martinez-Galan, Joaquina; Ales, Immacula JOURNAL OF CLINICAL ONCOLOGY 0732-183X (2019) DOI / 10.1200/jco.18.00089

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Article Stallion sperm freezing with sucrose extenders: A strategy to avoid permeable cryoprotectants Consuegra, C.; Crespo, F.; Bottrel, M.; Ortiz, I.; Dorado, J.; Diaz-Jimenez, M.; Pereira, B.; Hidalgo, M. ANIMAL REPRODUCTION SCIENCE 0378-4320 (2018) DOI / 10.1016/j.anireprosci.2018.02.013

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Article Afatinib restrains K-RAS-driven lung tumorigenesis Moll, Herwig P.; Pranz, Klemens; Musteanu, Monica; Grabner, Beatrice; Hruschka, Natascha; Mohrherr, Julian; Aigner, Petra; Stiedl, Patricia; Brcic, Luka; Laszlo, Viktoria; Schramek, Daniel; Moriggl, Richard; Eferl, Robert; Moldvay, Judit; Derso, Katalin; L SCIENCE TRANSLATIONAL MEDICINE 1946-6234 (2018) DOI / 10.1126/scitranslmed.aao2301 Bronze

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Article Pancreatic Cancer Risk in Relation to Lifetime Smoking Patterns, Tobacco Type, and Dose-Response Relationships Molina-Montes, Esther; Van Hoogstraten, Lisa; Gomez-Rubio, Paulina; Lohr, Matthias; Sharp, Linda; Molero, Xavier; Marquez, Mirari; Michalski, Christoph W.; Farre, Antoni; Perea, Jose; O'Rorke, Michael; Greenhalf, William; Ilzarbe, Lucas; Tardon, Adonina; G CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 1055-9965 (2020) DOI / 10.1158/1055-9965.epi-19-1027 Bronze

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Article Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin Rajeshkumar, N. V.; Yabuuchi, Shinichi; Pai, Shweta G.; de Oliveira, Elizabeth; Kamphorst, Jurre J.; Rabinowitz, Joshua D.; Tejero, Hector; Al-Shahrour, Fatima; Hidalgo, Manuel; Maitra, Anirban; Dang, Chi V. CLINICAL CANCER RESEARCH 1078-0432 (2017) DOI / 10.1158/1078-0432.ccr-17-1115 Green accepted, Bronze

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Article Motixafortide and Pembrolizumab Combined to Nanoliposomal Irinotecan, Fluorouracil, and Folinic Acid in Metastatic Pancreatic Cancer: The COMBAT/KEYNOTE-202 Trial Bockorny, Bruno; Macarulla, Teresa; Semenisty, Valerya; Borazanci, Erkut; Feliu, Jaime; Ponz-Sarvise, Mariano; Abad, David Gutierrez; Oberstein, Paul; Alistar, Angela; Munoz, Andres; Geva, Ravit; Guillen-Ponce, Carmen; Fernandez, Mercedes Salgado; Peled, A CLINICAL CANCER RESEARCH (2021) DOI / 10.1158/1078-0432.ccr-21-0929

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Article A Tricin Derivative from Deschampsia antarctica Desv. Inhibits Colorectal Carcinoma Growth and Liver Metastasis through the Induction of a Specific Immune Response Malvicini, Mariana; Gutierrez-Moraga, Ana; Rodriguez, Marcelo M.; Gomez-Bustillo, Sofia; Salazar, Lorena; Sunkel, Carlos; Nozal, Leonor; Salgado, Antonio; Hidalgo, Manuel; Lopez-Casas, Pedro P.; Luis Novella, Jose; Jose Vaquero, Juan; Alvarez-Builla, Julio MOLECULAR CANCER THERAPEUTICS 1535-7163 (2018) DOI / 10.1158/1535-7163.mct-17-0193 Bronze

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Article Discovery of New Targets to Control Metastasis in Pancreatic Cancer by Single-cell Transcriptomics Analysis of Circulating Tumor Cells Dimitrov-Markov, Spas; Perales-Paton, Javier; Bockorny, Bruno; Dopazo, Ana; Munoz, Manuel; Banos, Natalia; Bonilla, Victoria; Menendez, Camino; Duran, Yolanda; Huang, Ling; Perea, Sofia; Muthuswamy, Senthil K.; Al-Shahrour, Fatima; Lopez-Casas, Pedro P.; H MOLECULAR CANCER THERAPEUTICS 1535-7163 (2020) DOI / 10.1158/1535-7163.mct-19-1166 Bronze

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Article Consensus guidelines for diagnosis, treatment and follow-up of patients with pancreatic cancer in Spain Hidalgo, M.; Alvarez, R.; Gallego, J.; Guillen-Ponce, C.; Laquente, B.; Macarulla, T.; Munoz, A.; Salgado, M.; Vera, R.; Adeva, J.; Ales, I.; Arevalo, S.; Blazquez, J.; Calsina, A.; Carmona, A.; de Madaria, E.; Diaz, R.; Diez, L.; Fernandez, T.; de Paredes CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2017) DOI / 10.1007/s12094-016-1594-x Gold other, Green published

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Article A systems approach identifies time-dependent associations of multimorbidities with pancreatic cancer risk Gomez-Rubio, P.; Rosato, V.; Marquez, M.; Bosetti, C.; Molina-Montes, E.; Rava, M.; Pinero, J.; Michalski, C. W.; Farre, A.; Molero, X.; Lohr, M.; Ilzarbe, L.; Perea, J.; Greenhalf, W.; O'Rorke, M.; Tardon, A.; Gress, T.; Barbera, V. M.; Crnogorac-Jurcevic ANNALS OF ONCOLOGY 0923-7534 (2017) DOI / 10.1093/annonc/mdx167 Bronze, Green accepted, Green published

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Article Phase I Dose-Escalation and -Expansion Study of the BRAF Inhibitor Encorafenib (LGX818) in Metastatic BRAF-Mutant Melanoma Delord, Jean-Pierre; Robert, Caroline; Nyakas, Marta; McArthur, Grant A.; Kudchakar, Ragini; Mahipal, Amit; Yamada, Yasuhide; Sullivan, Ryan; Arance, Ana; Kefford, Richard F.; Carlino, Matteo S.; Hidalgo, Manuel; Gomez-Roca, Carlos; Michel, Daniela; Serout CLINICAL CANCER RESEARCH 1078-0432 (2017) DOI / 10.1158/1078-0432.ccr-16-2923 Green accepted, Bronze

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Article Evaluation of BGJ398, a Fibroblast Growth Factor Receptor 1-3 Kinase Inhibitor, in Patients With Advanced Solid Tumors Harboring Genetic Alterations in Fibroblast Growth Factor Receptors: Results of a Global Phase I, Dose-Escalation and Dose-Expansion Stud Nogova, Lucia; Sequist, Lecia V.; Garcia, Jose Manuel Perez; Andre, Fabrice; Delord, Jean-Pierre; Hidalgo, Manuel; Schellens, Jan H. M.; Cassier, Philippe A.; Camidge, D. Ross; Schuler, Martin; Vaishampayan, Ulka; Burris, Howard; Tian, G. Gary; Campone, Ma JOURNAL OF CLINICAL ONCOLOGY 0732-183X (2017) DOI / 10.1200/jco.2016.67.2048 Green published, Green accepted

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Article Clinical validation of prospective liquid biopsy monitoring in patients with wild-type RAS metastatic colorectal cancer treated with FOLFIRI-cetuximab Toledo, Rodrigo A.; Cubillo, Antonio; Vega, Estela; Garralda, Elena; Alvarez, Rafael; de la Varga, Lisardo U.; Pascual, Jesus R.; Sanchez, Gema; Sarno, Francesca; Prieto, Susana H.; Perea, Sofia; Lopez-Casas, Pedro P.; Lopez-Rios, Fernando; Hidalgo, Manuel ONCOTARGET 1949-2553 (2017) DOI / 10.18632/oncotarget.13311 Green published, Gold other

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Article Personalized RNA Medicine for Pancreatic Cancer Gilles, Maud-Emmanuelle; Hao, Liangliang; Huang, Ling; Rupaimoole, Rajesha; Lopez-Casas, Pedro P.; Pulver, Emilia; Jeong, Jong Cheol; Muthuswamy, Senthil K.; Hidalgo, Manuel; Bhatia, Sangeeta N.; Slack, Frank J. CLINICAL CANCER RESEARCH 1078-0432 (2018) DOI / 10.1158/1078-0432.ccr-17-2733 Green published, Bronze

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Review Pancreas Cancer Precision Treatment Using Avatar Mice from a Bioinformatics Perspective Perales-Paton, Javier; Pineiro-Yanez, Elena; Tejero, Hector; Lopez-Casas, Pedro P.; Hidalgo, Manuel; Gomez-Lopez, Gonzalo; Al-Shahrour, Fatima PUBLIC HEALTH GENOMICS 1662-4246 (2017) DOI / 10.1159/000479812 Bronze

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Article Reduced risk of pancreatic cancer associated with asthma and nasal allergies Gomez-Rubio, Paulina; Zock, Jan-Paul; Rava, Marta; Marquez, Mirari; Sharp, Linda; Hidalgo, Manuel; Carrato, Alfredo; Ilzarbe, Lucas; Michalski, Christoph; Molero, Xavier; Farre, Antoni; Perea, Jose; Greenhalf, William; O'Rorke, Michael; Tardon, Adonina; Gr GUT 0017-5749 (2017) DOI / 10.1136/gutjnl-2015-310442

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Article A phase 2 trial of personalized cytotoxic therapy based on tumor immunohistochemistry in previously treated metastatic pancreatic cancer patients Ramanathan, Ramesh K.; Weiss, Glen J.; Posner, Richard G.; Rajeshkumar, N. V.; Jameson, Gayle; Aziz, Meraj; Hoering, Antje; Bolejack, Vanessa; Maitra, Anirban; Fulk, Monica; Stites, Edward C.; Hlavacek, William S.; Gatalica, Zoran; Xiu, Joanne; Hidalgo, Ma JOURNAL OF GASTROINTESTINAL ONCOLOGY 2078-6891 (2017) DOI / 10.21037/jgo.2017.09.05 Green published

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Article VCN-01 disrupts pancreatic cancer stroma and exerts antitumor effects Bazan-Peregrino, Miriam; Garcia-Carbonero, Rocio; Laquente, Berta; Alvarez, Rafael; Mato-Berciano, Ana; Gimenez-Alejandre, Marta; Morgado, Sara; Rodriguez-Garcia, Alba; Maliandi, Maria, V; Riesco, M. Carmen; Moreno, Rafael; Ginesta, Mireia M.; Perez-Carrer JOURNAL FOR IMMUNOTHERAPY OF CANCER (2021) DOI / 10.1136/jitc-2021-003254 Gold

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Article Ruxolitinib plus capecitabine in advanced/metastatic pancreatic cancer after disease progression/intolerance to first-line therapy: JANUS 1 and 2 randomized phase III studies Hurwitz, Herbert; Van Cutsem, Eric; Bendell, Johanna; Hidalgo, Manuel; Li, Chung-Pin; Garrido Salvo, Marcelo; Macarulla, Teresa; Sahai, Vaibhav; Sama, Ashwin; Greeno, Edward; Yu, Kenneth H.; Verslype, Chris; Dawkins, Fitzroy; Walker, Chris; Clark, Jason; O INVESTIGATIONAL NEW DRUGS 0167-6997 (2018) DOI / 10.1007/s10637-018-0580-2 Green accepted

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Article Exome Sequencing of Plasma DNA Portrays the Mutation Landscape of Colorectal Cancer and Discovers Mutated VEGFR2 Receptors as Modulators of Antiangiogenic Therapies Toledo, Rodrigo A.; Garralda, Elena; Mitsi, Maria; Pons, Tirso; Monsech, Jorge; Vega, Estela; Otero, Alvaro; Albarran, Maria I.; Banos, Natalia; Duran, Yolanda; Bonilla, Victoria; Sarno, Francesca; Camacho-Artacho, Marta; Sanchez-Perez, Tania; Perea, Sofia CLINICAL CANCER RESEARCH 1078-0432 (2018) DOI / 10.1158/1078-0432.ccr-18-0103 Bronze

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Article OMTX705, a Novel FAP-Targeting ADC Demonstrates Activity in Chemotherapy and Pembrolizumab-Resistant Solid Tumor Models Fabre, Myriam; Ferrer, Cristina; Dominguez-Hormaetxe, Saioa; Bockorny, Bruno; Murias, Laura; Seifert, Oliver; Eisler, Stephan A.; Kontermann, Roland E.; Pfizenmaier, Klaus; Lee, So Young; Vivanco, Maria dM.; Lopez-Casas, Pedro P.; Perea, Sofia; Abbas, Muha CLINICAL CANCER RESEARCH 1078-0432 (2020) DOI / 10.1158/1078-0432.ccr-19-2238 Green published, Bronze

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Article A Phase I Clinical Trial and Independent Patient-Derived Xenograft Study of Combined Targeted Treatment with Dacomitinib and Figitumumab in Advanced Solid Tumors Calvo, Emiliano; Soria, Jean-Charles; Ma, Wen Wee; Wang, Tao; Bahleda, Rastilav; Tolcher, Anthony W.; Gernhardt, Diana; O'Connell, Joseph; Millham, Robert; Giri, Nagdeep; Wick, Michael J.; Adjei, Alex A.; Hidalgo, Manuel CLINICAL CANCER RESEARCH 1078-0432 (2017) DOI / 10.1158/1078-0432.ccr-15-2301 Bronze

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Article Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring MET Exon 14 Mutations and Overcomes Mutation-mediated Resistance to Type I MET Inhibitors in Nonclinical Models Engstrom, Lars D.; Aranda, Ruth; Lee, Matthew; Tovar, Elizabeth A.; Essenburg, Curt J.; Madaj, Zachary; Chiang, Harrah; Briere, David; Hallin, Jill; Lopez-Casas, Pedro P.; Banos, Natalia; Menendez, Camino; Hidalgo, Manuel; Tassell, Vanessa; Chao, Richard; CLINICAL CANCER RESEARCH 1078-0432 (2017) DOI / 10.1158/1078-0432.ccr-17-1192 Bronze

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Article First-In-Human Phase I Study Of A Dual mTOR Kinase And DNA-PK Inhibitor (CC-115) In Advanced Malignancy Munster, Pamela; Mita, Monica; Mahipal, Amit; Nemunaitis, John; Massard, Christophe; Mikkelsen, Tom; Cruz, Cristina; Paz-Ares, Luis; Hidalgo, Manuel; Rathkopf, Dana; Blumenschein, George, Jr.; Smith, David C.; Eichhorst, Barbara; Cloughesy, Tim; Filvaroff, CANCER MANAGEMENT AND RESEARCH 1179-1322 (2019) DOI / 10.2147/cmar.s208720 Gold DOAJ, Green published

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Review Adjuvant treatment for pancreatic ductal carcinoma Macarulla, T.; Fernandez, T.; Gallardo, M. E.; Hernando, O.; Lopez, A. M.; Hidalgo, M. CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2017) DOI / 10.1007/s12094-017-1683-5

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Article Nano-depletion of acrosome-damaged donkey sperm by using lectin peanut agglutinin (PNA)-magnetic nanoparticles Yousef, M. S.; Lopez-Lorente, A., I; Diaz-Jimenez, M.; Consuegra, C.; Dorado, J.; Pereira, B.; Ortiz, I; Cardenas, S.; Hidalgo, M. THERIOGENOLOGY 0093-691X (2020) DOI / 10.1016/j.theriogenology.2020.04.011

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Article Sperm morphometry is affected by increased inbreeding in the Retinta cattle breed: A molecular approach Teran, Ester; Azcona, Florencia; Ramon, Manuel; Molina, Antonio; Dorado, Jesus; Hidalgo, Manuel; Ross, Pablo; Goszczynski, Daniel; Demyda-Peyras, Sebastian MOLECULAR REPRODUCTION AND DEVELOPMENT 1040-452X (2021) DOI / 10.1002/mrd.23475

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Article Gallbladder disease and pancreatic cancer risk: a multicentric case-control European study Rosato, V; Gomez-Rubio, P.; Molina-Montes, E.; Marquez, M.; Lohr, M.; O'Rorke, M.; Michalski, C. W.; Molero, X.; Farre, A.; Perea, J.; Kleeff, J.; Crnogorac-Jurcevic, T.; Greenhalf, W.; Ilzarbe, L.; Tardon, A.; Gress, T.; Barbera, V. M.; Dominguez-Munoz, E EUROPEAN JOURNAL OF CANCER PREVENTION 0959-8278 (2021) DOI / 10.1097/cej.0000000000000588

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Article First-in-Human Phase I Study of Single-agent Vanucizumab, A First-in-Class Bispecific Anti-Angiopoietin-2/Anti-VEGF-A Antibody, in Adult Patients with Advanced Solid Tumors Hidalgo, Manuel; Martinez-Garcia, Maria; Le Tourneau, Christophe; Massard, Christophe; Garralda, Elena; Boni, Valentina; Taus, Alvaro; Albanell, Joan; Sablin, Marie-Paule; Alt, Marie; Bahleda, Ratislav; Varga, Andrea; Boetsch, Christophe; Franjkovic, Izold CLINICAL CANCER RESEARCH 1078-0432 (2018) DOI / 10.1158/1078-0432.ccr-17-1588 Bronze

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Review Management of hyperbilirubinaemia in pancreatic cancer patients Alvarez, R.; Carrato, A.; Adeva, J.; Ales, I.; Prados, S.; Valladares, M.; Macarulla, T.; Munoz, A.; Hidalgo, M. EUROPEAN JOURNAL OF CANCER 0959-8049 (2018) DOI / 10.1016/j.ejca.2018.01.078