Trabajos de Oscar López

Trabajos de Nombre

Pharmacology & Toxicology


  Listando 11 trabajos del autor/autora 38
Lista de trabajos en el área Pharmacology & Toxicology
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Article Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors Ahuja-Casarin, Ana I.; Merino-Montiel, Penelope; Vega-Baez, Jose Luis; Montiel-Smith, Sara; Fernandes, Miguel X.; Lagunes, Irene; Maya, Ines; Padron, Jose M.; Lopez, Oscar; Fernandez-Bolanos, Jose G. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 1475-6366 (2021) DOI / 10.1080/14756366.2020.1847101 Green published, Gold
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Article Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors Roldan-Pena, Jesus M.; Romero-Real, Valle; Hicke, Javier; Maya, Ines; Franconetti, Antonio; Lagunes, Irene; Padron, Jose M.; Petralla, Sabrina; Poeta, Eleonora; Naldi, Marina; Bartolini, Manuela; Monti, Barbara; Bolognesi, Maria L.; Lopez, Oscar; Fernandez EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 0223-5234 (2019) DOI / 10.1016/j.ejmech.2019.07.053
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Article Straightforward access to novel mitochondriotropics derived from 2-arylethanol as potent and selective antiproliferative agents Hicke, Francisco J.; Puerta, Adrian; Dinic, Jelena; Pesic, Milica; Padron, Jose M.; Lopez, Oscar; Fernandez-Bolanos, Jose G. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 0223-5234 (2021) DOI / 10.1016/j.ejmech.2021.113980
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Review Metal- and metalloid-based compounds to target and reverse cancer multidrug resistance Valente, Andreia; Podolski-Renic, Ana; Poetsch, Isabella; Filipovic, Nenad; Lopez, Oscar; Turel, Iztok; Heffeter, Petra DRUG RESISTANCE UPDATES 1368-7646 (2021) DOI / 10.1016/j.drup.2021.100778 Hybrid, Green published
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Article Ugi Reaction Synthesis of Oxindole-Lactam Hybrids as Selective Butyrylcholinesterase Inhibitors Brandao, Pedro; Lopez, Oscar; Leitzbach, Luisa; Stark, Holger; Fernandez-Bolanos, Jose G.; Burke, Anthony J.; Pineiro, Marta ACS MEDICINAL CHEMISTRY LETTERS 1948-5875 (2021) DOI / 10.1021/acsmedchemlett.1c00344
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Article Glucosylpolyphenols as Inhibitors of A beta-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease de Matos, Ana M.; Blazquez-Sanchez, M. Teresa; Bento-Oliveira, Andreia; de Almeida, Rodrigo F. M.; Nunes, Rafael; Lopes, Pedro E. M.; Machuqueiro, Miguel; Cristovao, Joana S.; Gomes, Claudio M.; Souza, Cleide S.; El Idrissi, Imane G.; Colabufo, Nicola A.; JOURNAL OF MEDICINAL CHEMISTRY 0022-2623 (2020) DOI / 10.1021/acs.jmedchem.0c00841 Green accepted
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Article New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents Roldan-Pena, Jesus M.; Alejandre-Ramos, Daniel; Lopez, Oscar; Maya, Ines; Lagunes, Irene; Padron, Jose M.; Pena-Altamira, Luis Emiliano; Bartolini, Manuela; Monti, Barbara; Bolognesi, Maria L.; Fernandez-Bolanos, Jose G. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 0223-5234 (2017) DOI / 10.1016/j.ejmech.2017.06.048
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Article Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and A beta(1-42)-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells de Matos, Ana M.; Martins, Alice; Man, Teresa; Evans, David; Walter, Magnus; Oliveira, Maria Conceicao; Lopez, Oscar; Fernandez-Bolanos, Jose G.; Datwyler, Philipp; Ernst, Beat; Macedo, M. Paula; Contino, Marialessandra; Colabufo, Nicola A.; Rauter, Amelia PHARMACEUTICALS (2019) DOI / 10.3390/ph12020098 Gold DOAJ, Green published
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Article Development of tacrine clusters as positively cooperative systems for the inhibition of acetylcholinesterase Santos Evangelista, Tereza Cristina; Lopez, Oscar; Baptista Ferreira, Sabrina; Fernandez-Bolanos, Jose G.; Sydnes, Magne O.; Lindback, Emil JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY 1475-6366 (2021) DOI / 10.1080/14756366.2021.1954917 Green published, Gold
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Article Masked Phenolic-Selenium Conjugates: Potent and Selective Antiproliferative Agents Overcoming P-gp Resistance Begines, Paloma; Sevilla-Horrillo, Lucia; Puerta, Adrian; Puckett, Rebecca; Bayort, Samuel; Lagunes, Irene; Maya, Ines; Padron, Jose M.; Lopez, Oscar; Fernandez-Bolanos, Jose G. PHARMACEUTICALS (2020) DOI / 10.3390/ph13110358 Gold, Green published
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Article In silico, NMR and pharmacological evaluation of an hydroxyoxindole cholinesterase inhibitor Bacalhau, Patricia; Fernandes, Luis; Rosario Martins, M.; Candeias, Fatima; Carreiro, Elisabete P.; Lopez, Oscar; Teresa Caldeira, A.; Totobenazara, Jane; Guedes, Rita C.; Burke, Anthony J. BIOORGANIC & MEDICINAL CHEMISTRY 0968-0896 (2019) DOI / 10.1016/j.bmc.2018.12.007 Green published