Trabajos de Enrique De Alava

Trabajos de Nombre

Clinical Medicine


  Listando 29 trabajos del autor/autora 38
Lista de trabajos en el área Clinical Medicine
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Article DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma Sheffield, Nathan C.; Pierron, Gaelle; Klughammer, Johanna; Datlinger, Paul; Schoenegger, Andreas; Schuster, Michael; Hadler, Johanna; Surdez, Didier; Guillemot, Delphine; Lapouble, Eve; Freneaux, Paul; Champigneulle, Jacqueline; Bouvier, Raymonde; Walder, NATURE MEDICINE 1078-8956 (2017) DOI / 10.1038/nm.4273 Green accepted
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Review Ewing Sarcoma-Diagnosis, Treatment, Clinical Challenges and Future Perspectives Zoellner, Stefan K.; Amatruda, James E.; Bauer, Sebastian; Collaud, Stephane; de Alava, Enrique; DuBois, Steven G.; Hardes, Jendrik; Hartmann, Wolfgang; Kovar, Heinrich; Metzler, Markus; Shulman, David S.; Streitbuerger, Arne; Timmermann, Beate; Toretsky, JOURNAL OF CLINICAL MEDICINE (2021) DOI / 10.3390/jcm10081685 Gold DOAJ, Green published
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Article RING1B recruits EWSR1-FLI1 and cooperates in the remodeling of chromatin necessary for Ewing sarcoma tumorigenesis Sanchez-Molina, Sara; Figuerola-Bou, Elisabet; Blanco, Enrique; Sanchez-Jimenez, Maria; Taboas, Pablo; Gomez, Soledad; Ballare, Cecilia; Garcia-Dominguez, Daniel J.; Prada, Estela; Hontecillas-Prieto, Lourdes; Carcaboso, Angel M.; Tirado, Oscar M.; Hernand SCIENCE ADVANCES 2375-2548 (2020) DOI / 10.1126/sciadv.aba3058 Gold DOAJ, Green published
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Article Ewing sarcoma Gruenewald, Thomas G. P.; Cidre-Aranaz, Florencia; Surdez, Didier; Tomazou, Eleni M.; de Alava, Enrique; Kovar, Heinrich; Sorensen, Poul H.; Delattre, Olivier; Dirksen, Uta NATURE REVIEWS DISEASE PRIMERS 2056-676X (2018) DOI / 10.1038/s41572-018-0003-x
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Article EphA2 receptor is a key player in the metastatic onset of Ewing sarcoma Garcia-Monclus, Silvia; Lopez-Alemany, Roser; Almacellas-Rabaiget, Olga; Herrero-Martin, David; Huertas-Martinez, Juan; Lagares-Tena, Laura; Alba-Pavon, Piedad; Hontecillas-Prieto, Lourdes; Mora, Jaume; de Alava, Enrique; Rello-Varona, Santi; Giangrande, P INTERNATIONAL JOURNAL OF CANCER 0020-7136 (2018) DOI / 10.1002/ijc.31405 Bronze, Green accepted
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Article Pazopanib for treatment of advanced extraskeletal myxoid chondrosarcoma: a multicentre, single-arm, phase 2 trial Stacchiotti, Silvia; Ferrari, Stefano; Redondo, Andres; Hindi-Muniz, Nadia; Palmerini, Emanuela; Salgado, Maria Angeles Vaz; Frezza, Anna Maria; Casali, Paolo Giovanni; Gutierrez, Antonio; Lopez-Pousa, Antonio; Grignani, Giovanni; Italiano, Antoine; Lecesn LANCET ONCOLOGY 1470-2045 (2019) DOI / 10.1016/s1470-2045(19)30319-5
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Article DNA methylation profiling identifies PTRF/Cavin-1 as a novel tumor suppressor in Ewing sarcoma when co-expressed with caveolin-1 Huertas-Martinez, Juan; Court, Franck; Rello-Varona, Santiago; Herrero-Martin, David; Almacellas-Rabaiget, Olga; Sainz-Jaspeado, Miguel; Garcia-Monclus, Silvia; Lagares-Tena, Laura; Buj, Raquel; Hontecillas-Prieto, Lourdes; Sastre, Ana; Azorin, Daniel; San CANCER LETTERS 0304-3835 (2017) DOI / 10.1016/j.canlet.2016.11.020
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Article LOXL2 promotes oncogenic progression in alveolar rhabdomyosarcoma independently of its catalytic activity Almacellas-Rabaiget, Olga; Monaco, Paola; Huertas-Martinez, Juan; Garcia-Monclus, Silvia; Chicon-Bosch, Mariona; Maqueda-Marcos, Susana; Fabra-Heredia, Isabel; Herrero-Martin, David; Rello-Varona, Santiago; de Alava, Enrique; Lopez-Alemany, Roser; Giangran CANCER LETTERS 0304-3835 (2020) DOI / 10.1016/j.canlet.2019.12.040
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Article Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets Baldauf, Michaela C.; Orth, Martin F.; Dallmayer, Marlene; Marchetto, Aruna; Gerke, Julia S.; Rubio, Rebeca Alba; Kiran, Merve M.; Musa, Julian; Knott, Maximilian M. L.; Ohmura, Shunya; Li, Jing; Akpolat, Nusret; Akatli, Ayse N.; Ozen, Ozlem; Dirksen, Uta; ONCOTARGET 1949-2553 (2018) DOI / 10.18632/oncotarget.20098 Gold other, Green published
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Article Pazopanib for treatment of typical solitary fibrous tumours: a multicentre, single-arm, phase 2 trial Martin-Broto, Javier; Cruz, Josefina; Penel, Nicolas; Le Cesne, Axel; Hindi, Nadia; Luna, Pablo; Moura, David S.; Bernabeu, Daniel; de Alava, Enrique; Lopez-Guerrero, Jose Antonio; Dopazo, Joaquin; Pena-Chilet, Maria; Gutierrez, Antonio; Collini, Paola; Ka LANCET ONCOLOGY 1470-2045 (2020) DOI / 10.1016/s1470-2045(19)30826-5
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Article Pazopanib for treatment of advanced malignant and dedifferentiated solitary fibrous tumour: a multicentre, single-arm, phase 2 trial Martin-Broto, Javier; Stacchiotti, Silvia; Lopez-Pousa, Antonio; Redondo, Andres; Bernabeu, Daniel; de Alava, Enrique; Casali, Paolo G.; Italiano, Antoine; Gutierrez, Antonio; Moura, David S.; Pena-Chilet, Maria; Diaz-Martin, Juan; Biscuola, Michele; Taron LANCET ONCOLOGY 1470-2045 (2019) DOI / 10.1016/s1470-2045(18)30676-4
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Article Sarcoma European and Latin American Network (SELNET) Recommendations on Prioritization in Sarcoma Care During the COVID-19 Pandemic Martin-Broto, Javier; Hindi, Nadia; Aguiar, Samuel, Jr.; Badilla-Gonzalez, Ronald; Castro-Oliden, Victor; Chacon, Matias; Correa-Generoso, Raquel; de Alava, Enrique; Donati, Davide Maria; Eriksson, Mikael; Falla-Jimenez, Martin; German, Gisela; Gobo Silva, ONCOLOGIST 1083-7159 (2020) DOI / 10.1634/theoncologist.2020-0516 Hybrid, Green published
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Article Multidisciplinary consensus on optimising the detection of NTRK gene alterations in tumours Garrido, P.; Hladun, R.; de Alava, E.; Alvarez, R.; Bautista, F.; Lopez-Rios, F.; Colomer, R.; Rojo, F. CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2021) DOI / 10.1007/s12094-021-02558-0 Gold other
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Article Nivolumab and sunitinib combination in advanced soft tissue sarcomas: a multicenter, single-arm, phase Ib/II trial Martin-Broto, Javier; Hindi, Nadia; Grignani, Giovanni; Martinez-Trufero, Javier; Redondo, Andres; Valverde, Claudia; Stacchiotti, Silvia; Lopez-Pousa, Antonio; D'Ambrosio, Lorenzo; Gutierrez, Antonio; Perez-Vega, Herminia; Encinas-Tobajas, Victor; de Alav JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020) DOI / 10.1136/jitc-2020-001561 Gold DOAJ, Green published
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Article Liquid biopsy in oncology: a consensus statement of the Spanish Society of Pathology and the Spanish Society of Medical Oncology Remon, J.; Garcia-Campelo, R.; de Alava, E.; Vera, R.; Rodriguez-Peralto, J. L.; Rodriguez-Lescure, A.; Bellosillo, B.; Garrido, P.; Rojo, F.; Alvarez-Alegret, R. CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2020) DOI / 10.1007/s12094-019-02211-x Green published, Gold other
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Review Molecular diagnosis in non-small-cell lung cancer: expert opinion on ALK and ROS1 testing Conde, Esther; Rojo, Federico; Gomez, Javier; Belen Enguita, Ana; Abdulkader, Ihab; Gonzalez, Ana; Lozano, Dolores; Mancheno, Nuria; Salas, Clara; Salido, Marta; Salido-Ruiz, Eduardo; de Alava, Enrique JOURNAL OF CLINICAL PATHOLOGY 0021-9746 (2021) DOI / 10.1136/jclinpath-2021-207490 Green published, Hybrid
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Letter Are EWSR1-NFATc2-positive sarcomas really Ewing sarcomas? Baldauf, Michaela C.; Gerke, Julia S.; Orth, Martin F.; Dallmayer, Marlene; Baumhoer, Daniel; de Alava, Enrique; Hartmann, Wolfgang; Kirchner, Thomas; Gruenewald, Thomas G. P. MODERN PATHOLOGY 0893-3952 (2018) DOI / 10.1038/s41379-018-0009-7 Bronze
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Article Hippo pathway effectors YAP1/TAZ induce an EWS-FLI1-opposing gene signature and associate with disease progression in Ewing sarcoma Rodriguez-Nunez, Pablo; Romero-Perez, Laura; Amaral, Ana T.; Puerto-Camacho, Pilar; Jordan, Carmen; Marcilla, David; Gruenewald, Thomas G. P.; Alonso, Javier; de Alava, Enrique; Diaz-Martin, Juan JOURNAL OF PATHOLOGY 0022-3417 (2020) DOI / 10.1002/path.5379 Green published, Gold other
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Article E3 ubiquitin ligase Atrogin-1 mediates adaptive resistance to KIT-targeted inhibition in gastrointestinal stromal tumor Garcia-Valverde, Alfonso; Rosell, Jordi; Sayols, Sergi; Gomez-Peregrina, David; Pilco-Janeta, Daniel F.; Olivares-Rivas, Ivan; de Alava, Enrique; Maurel, Joan; Rubio-Casadevall, Jordi; Esteve, Anna; Gut, Marta; Valverde, Claudia; Barretina, Jordi; Carles, ONCOGENE 0950-9232 (2021) DOI / 10.1038/s41388-021-02049-0
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Article Proposal for the creation of a national strategy for precision medicine in cancer: a position statement of SEOM, SEAP, and SEFH Garrido, P.; Aldaz, A.; Vera, R.; Calleja, M. A.; de Alava, E.; Martin, M.; Matias-Guiu, X.; Palacios, J. CLINICAL & TRANSLATIONAL ONCOLOGY 1699-048X (2018) DOI / 10.1007/s12094-017-1740-0 Green published, Gold other
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Article Evaluation of NAB2-STAT6 Fusion Variants and Other Molecular Alterations as Prognostic Biomarkers in a Case Series of 83 Solitary Fibrous Tumors Salguero-Aranda, Carmen; Martinez-Reguera, Paula; Marcilla, David; de Alava, Enrique; Diaz-Martin, Juan CANCERS (2021) DOI / 10.3390/cancers13205237 Gold, Green published
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Article GEIS-21: a multicentric phase II study of intensive chemotherapy including gemcitabine and docetaxel for the treatment of Ewing sarcoma of children and adults: a report from the Spanish sarcoma group (GEIS) Mora, J.; Castaneda, A.; Perez-Jaume, S.; Lopez-Pousa, A.; Maradiegue, E.; Valverde, C.; Martin-Broto, J.; Garcia del Muro, X.; Cruz, O.; Cruz, J.; Martinez-Trufero, J.; Maurel, J.; Vaz, M. A.; de Alava, E.; de Torres, C. BRITISH JOURNAL OF CANCER 0007-0920 (2017) DOI / 10.1038/bjc.2017.252 Gold other, Green published
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Editorial Material What's in a name? Molecular subclassification of sarcomas creates fresh challenges Diaz-Martin, Juan; Biscuola, Michele; Benoit, Jonatan; Marcilla, David; Civantos, Gema; de Alava, Enrique JOURNAL OF PATHOLOGY 0022-3417 (2019) DOI / 10.1002/path.5206 Bronze
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Article An inducible ectopic expression system of EWSR1-FLI1 as a tool for understanding Ewing sarcoma oncogenesis Garcia-Dominguez, Daniel J.; Hontecillas-Prieto, Lourdes; Andres Leon, Eduardo; Sanchez-Molina, Sara; Rodriguez-Nunez, Pablo; Moron, Francisco J.; Hajji, Nabil; Mackintosh, Carlos; de Alava, Enrique PLOS ONE 1932-6203 (2020) DOI / 10.1371/journal.pone.0234243 Green published, Gold
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Article Preclinical Efficacy of Endoglin-Targeting Antibody-Drug Conjugates for the Treatment of Ewing Sarcoma Puerto-Camacho, Pilar; Teresa Amaral, Ana; Lamhamedi-Cherradi, Salah-Eddine; Menegaz, Brian A.; Castillo-Ecija, Helena; Luis Ordonez, Jose; Dominguez, Saioa; Jordan-Perez, Carmen; Diaz-Martin, Juan; Romero-Perez, Laura; Lopez-Alvarez, Maria; Civantos-Juber CLINICAL CANCER RESEARCH 1078-0432 (2019) DOI / 10.1158/1078-0432.ccr-18-0936 Green accepted, Bronze
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Article Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma Garcia-Dominguez, Daniel J.; Hajji, Nabil; Sanchez-Molina, Sara; Figuerola-Bou, Elisabet; de Pablos, Rocio M.; Espinosa-Oliva, Ana M.; Andres-Leon, Eduardo; Terron-Camero, Laura Carmen; Flores-Campos, Rocio; Pascual-Pasto, Guillem; Robles, Maria Jose; Carc ONCOGENE 0950-9232 (2021) DOI / 10.1038/s41388-021-01974-4 Hybrid
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Article DNA methylation profiling distinguishes Ewing-like sarcoma with EWSR1-NFATc2 fusion from Ewing sarcoma Koelsche, Christian; Kriegsmann, Mark; Kommoss, Felix K. F.; Stichel, Damian; Kriegsmann, Katharina; Vokuhl, Christian; Gruenewald, Thomas G. P.; Romero-Perez, Laura; Kirchner, Thomas; de Alava, Enrique; Diaz-Martin, Juan; Hartmann, Wolfgang; Baumhoer, Dan JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY 0171-5216 (2019) DOI / 10.1007/s00432-019-02895-2 Green accepted
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Article Both Epimutations and Chromosome Aberrations Affect Multiple Imprinted Loci in Aggressive Wilms Tumors Pignata, Laura; Palumbo, Orazio; Cerrato, Flavia; Acurzio, Basilia; de Alava, Enrique; Roma, Josep; Gallego, Soledad; Mora, Jaume; Carella, Massimo; Riccio, Andrea; Verde, Gaetano CANCERS (2020) DOI / 10.3390/cancers12113411 Gold DOAJ, Green published
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Article Multidrug resistance transporter profile reveals MDR3 as a marker for stratification of blastemal Wilms tumour patients Hontecillas-Prieto, Lourdes; Garcia-Dominguez, Daniel J.; Pascual Vaca, Diego; Garcia-Mejias, Rosa; Marcilla, David; Ramirez-Villar, Gema L.; Saez, Carmen; de Alava, Enrique ONCOTARGET 1949-2553 (2017) DOI / 10.18632/oncotarget.14491 Green published, Gold other